Biochemical innovations for expanding the therapeutics window of ADCs
Speaker: Dr. Christine Köhler, Co-founder, Director Antibody Engineering
Date & Time: August 10 at 3:10 – 3:30 PM
Talk: Biochemical innovations for expanding the therapeutics window of ADCs
- Outstanding chemistry: Efficient and stable hydrophilic clickchemistry for reduced off- target toxicity
- Unique Payload platform: Phosphonate-substituted tetrazines enable highly hydrophilic bioconjugation
- Positioning intelligence: Selectable conjugation position allows further optimization of Efficay, PK & internalization
- Highly efficient ADCs: Expanding the therapeutic window with increased efficacy and reduced-off target toxicity